Glycosyl compounds
Medchemexpress LLC D-GsMTx4 | 99.44% | 4095.84 | 2 MG
D-GsMTx4 is a spider peptide, serving as the D enantiomer of GsMTx4. It functions as an inhibitor of the mechanosensitive ion channel Piezo2, effectively reducing [Ca2+]i elevation and modulating the mTOR and PI3K-Akt signaling pathways. This peptide has shown to inhibit mechanical allodynia and thermal hyperalgesia, making it a valuable tool for research into conditions such as mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Inhibits Piezo2-mediated mechanosensitive inward currents
- Decreases phosphorylation levels in mTOR and PI3K-Akt pathways
- Inhibits mechanical stimulation-evoked [Ca2+]i increases
- Reduces mechanical allodynia and thermal hyperalgesia
Medchemexpress LLC 5-nitro-6-(3-nitrophenyl)-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile | 685121-45-3 | MFCD04111032; MFCD31735118; MFCD32015709 | 99.9% | 354.20 g/mol | C13H5F3N4O5 | 10MM 1ML
SynuClean-D is a small-molecule inhibitor of α-synuclein aggregation used in research to disrupt amyloid fibrils and inhibit fibril propagation; it has shown neuroprotective effects in Parkinson's disease models.
- Inhibits α-synuclein aggregation in vitro.
- Disrupts mature amyloid fibrils.
- Prevents fibril propagation and seeding.
- Reduces dopaminergic neuron degeneration in animal models.
- Available as a 10 mM solution in DMSO and in multiple solid quantities.
- High assay purity (≈99.9%).
- Molecular formula C13H5F3N4O5, molecular weight 354.20 g/mol.
Medchemexpress LLC Cyanidin-3-O-galactoside chloride | 27661-36-5 | 99.2% | 484.84 | 1 MG
Cyanidin-3-O-galactoside chloride, also known as Ideain chloride, is a component found in the extract peel of hawthorn fruit (EPHF). EPHF exhibits strong Acetylcholinesterase (AChE) inhibitory activity, and also demonstrates significant antioxidant properties. It shows cytotoxicity against MCF-7 and SKOV-3 human tumor cell lines in a dose-dependent manner.
- Exhibits strong AChE inhibitory activity
- Demonstrates strong antioxidant activity
- Shows high cytotoxicity against MCF-7 and SKOV-3 human tumor cell lines
Medchemexpress LLC D-GsMTx4 | 99.4% | 4095.84 | 100 UG
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It acts as an inhibitor of the mechanosensitive ion channel Piezo2. It inhibits [Ca2+]i elevation and also impacts the mTOR and PI3K-Akt signaling pathways. D-GsMTx4 has been shown to inhibit mechanical allodynia and thermal hyperalgesia. It is suitable for research in areas such as mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Inhibits the mechanosensitive ion channel Piezo2.
- Inhibits [Ca2+]i elevation.
- Inhibits mTOR and PI3K-Akt signaling pathways.
- Inhibits mechanical allodynia and thermal hyperalgesia.
- Suitable for research on mechanical stress, chronic pain, and idiopathic pulmonary fibrosis.
- Decreases phosphorylation levels of proteins in the mTOR and PI3K-Akt signaling pathways in primary human lung fibroblasts.
Cayman Chemical n-DodecylD-maltosIde 5g
A non-ionic detergent commonly used to solubilize membrane-associated proteins; helps retain the native conformation and activity of membrane-associated proteins, and facilitates the reforming of these proteins after denaturation
![eMolecules 13992-25-1 | 1-Azido-1-deoxy-b-D-glucopyranoside tetraacetate | Chem-Impex373.318 | C14H19N3O9 | 99.000 | CC(=O)OCC1OC(N=[N+]=[N-])C(OC(C)=O)C(OC(C)=O)C1OC(C)=O | 1g | 112769746](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502178092.JPG-250.jpg)
eMolecules 13992-25-1 | 1-Azido-1-deoxy-b-D-glucopyranoside tetraacetate | Chem-Impex373.318 | C14H19N3O9 | 99.000 | CC(=O)OCC1OC(N=[N+]=[N-])C(OC(C)=O)C(OC(C)=O)C1OC(C)=O | 1g | 112769746
1-Azido-1-deoxy-b-D-glucopyranoside tetraacetate | Chem-Impex | 13992-25-1373.318 | C14H19N3O9 | 99.000 | CC(=O)OCC1OC(N=[N+]=[N-])C(OC(C)=O)C(OC(C)=O)C1OC(C)=O | 1g | 112769746
Selleck Chemical LLC Rebaudioside D S3259-1mg
Rebaudioside D (Reb D) is one of the several glycosides (SGs) found in the leaves of Stevia rebaudiana (Bertoni) which has been identified as a potential sweetener
Medchemexpress LLC beta-Catenin Human 10ug
Beta-Catenin protein is an important component of the canonical Wnt pathway and regulates cellular processes In the absence of Wnt it complexes with AXIN1 AXIN2 APC CSNK1A1 and GSK3B to promote CTNNB1 phosphorylation and degradation beta-Catenin Protein Human (sf9 His-GST) is the recombinant human-derived beta-Catenin protein expressed by Sf9 insect cells with N-His N-GST labeled tag
Medchemexpress LLC 1-deazaadenosine | 14432-09-8 | MFCD22683837 | 98.9% | 266.25 | C11H14N4O4 | 1 MG
1-Deazaadenosine is a nucleoside analogue used as a biochemical research reagent that potently inhibits adenosine deaminase (ADA) and is used in in vitro studies of ADA-related pathways and lymphoproliferative disorders.
- Potent adenosine deaminase (ADA) inhibitor with Ki = 0.66 μM.
- High purity: 98.9%.
- Molecular weight: 266.25 g/mol.
- Chemical formula: C11H14N4O4.
- White to off-white solid suitable for laboratory use.
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (up to 6 months) or -20°C (up to 1 month).
Cayman Chemical 9Nitrooleate Fatty Acids and D
A novel endogenous lipid signaling molecule; nitration product of oleic acid in vivo mediated by peroxynitrite, acidified nitrite, or myeloperoxidase (in the presence of H2O2 and nitrite)
Medchemexpress LLC SIRP beta Mouse HE 50ug | 50ug
SIRP-beta (Sirpb CD172b) is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily SIRP family members are receptor-type transmembrane glycoproteins Sirpb was found to interact with TYROBP/DAP12 a transmembrane adaptor protein bearing immunoreceptor tyrosine-based activation motifs resulting in the tyrosine phosphorylation of DAP12 and the subsequent recruitment of Syk to the Sirpb-DAP12 complex Sirpb is also implicated as a positive regulator of hematopoietic cells SIRP beta Protein Mouse (HEK293 His) is the recombinant mouse-derived SIRP beta protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Nerve growth factor-β (beta-NGF) | 86923-98-0 | MFCD00164982 | >90.0% | 20UG
Recombinant rat beta-nerve growth factor (beta-NGF) expressed in HEK293 cells and purified with a C-terminal His tag. Supplied lyophilized in PBS with 6% trehalose, this biologically active protein supports neuronal survival and differentiation and is suitable for in vitro cell culture assays.
- Expressed in HEK293 cells.
- C-terminal His tag for purification.
- Lyophilized from PBS with 6% trehalose, pH 7.4.
- Predicted molecular mass ~26.4 kDa.
- Purity greater than 90% by reducing SDS-PAGE.
- Endotoxin level <1 EU/μg as determined by LAL.
- Stable at -20°C for long-term storage; aliquot and freeze for extended use.
- Activity demonstrated in a TF-1 cell proliferation assay.
- Available in multiple microgram quantities for research use.
Medchemexpress LLC S-nitroso-N-acetylpenicillamine | 79032-48-7 | MFCD00272624 | 95.0% | 220.25 | C7H12N2O4S | 5 MG
D-SNAP (S-nitroso-N-acetylpenicillamine) is a nitrosothiol reagent used as a nitric oxide donor and fluorescent probe in biochemical and cellular research. Provided in a milligram-scale vial at research-grade purity, it is intended for laboratory assays and should be handled and stored per the safety data sheet.
- Acts as a nitric oxide donor for in vitro and cellular experiments.
- Functions as a fluorescent reagent for detection and labeling applications.
- High purity suitable for research use.
- Molecular weight 220.25 g/mol and formula C7H12N2O4S.
- Available in milligram-scale vials for small-scale experiments.